PYRIDINE Project - SCP
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PYRIDINE Project - SCP   🔬

(Structural Characterization Platform)

The structural characterization platform of the PYRIDINE project is equipped with some of the most advanced instruments in the world to perform the most thorough analysis of your samples:

Size Exclusion / Gel Permeation Chromatography (SEC / GPC)

Image of the GPCs

GPC, a sub-category of SEC, is an extremely useful method to characterize molecular weight distribution of a sample (Mn, Mw, Mv, Mz, Mz+1, PDI, ...). It can also be used for branching characterization with the viscometer.

Preparative GPC

Image of the preparative GPC

Preparative GPC allows the separation by means of GPC. This allows to separate a polymer with an initially broad weight distribution (PDI > 2) into many fractions with each a very narrow molecular weight distribution (typically PDI ~1.1-1.2)

AF4

Image of the AF4

Asymmetric Flow Field-Flow Fractionation (AF4) is a powerful technique based on size exclusion principles in a microfluidic channel dictated by laminar parabolic flow. As opposed to common size exclusion chromatography techniques, samples can be either dissolved or dispersed in a solvent (water, THF, ...) with the use of a surfactant, and smaller particles/molecules will flow faster and come out first (in regular FFF mode). Combined to a multi-angle light scattering (MALS, 20 angles) from 7° to 173°, an online DLS and a UV-vis DAD detector, it is perfectly suitable for the fractionation and characterization of a large variety of samples (molecules, polymers, proteins, inorgnaic particles, ...).

Particle Size and Zeta Potential Analyzer - Dynamic and Electrophoretic Light Scattering (DLS-ELS)

Image of the DLS/ELS/PALS

The Brookhaven Omni, combined with its autotitrator, is capable of performing many types of measurements to determine either the size distribution (through dynamic light scattering, DLS) or the zeta potential (through either electrophoretic light scatering, ELS, or phase angle light scattering, PALS). With the autotitrator, it is possible to automate pH-dependent measurement such as the determination of the isoelectric point (by ELS/PALS) or to look at colloïdal stability vs pH (by DLS).

X-Ray Diffraction (XRD)

Image of the XRD D8 Advance

The XRD Brüker D8 Advance is a powder XRD instrument to measure powder XRD diffractograms of samples. Very useful for the determination of polymer crystallinity or to follow any changes on a diffracting solid (either organic or inoganic).